Your patients are all different and deserve a treatment with the flexibility to fit their individual needs and preferences. Use the guidelines and dosing calculator below to initiate a patient's Hizentra therapy. Adjust the dose based on clinical response and serum immunoglobulin G (IgG) trough levels.
Find information regarding self-infusion training to help your patients get started on Hizentra
The Hizentra dosing calculator can help you rapidly determine an accurate recommended dose of Hizentra for your patients.
Simply complete the fields below and Calculate.
Based on an IVIg dose of [number] grams every [frequency] weeks, your Hizentra dose every [infusion] day(s) will be:
Here is the formula used by the calculator to determine a weekly dose:
Over time, the dose may have to be adjusted to achieve the desired results. To determine if a dose adjustment is needed, measure the patient's serum IgG trough level 2 to 3 months after transitioning to Hizentra. To learn how to adjust the dose, please see the full Prescribing Information.
The goal is to achieve a systemic serum IgG exposure (area under the concentration-time curve) not inferior to that of the previous IVIg treatment (if applicable).
Here are the formulas for converting a weekly Hizentra dose to other frequencies:
Hizentra should be administered subcutaneously only. Do not administer intravenously. Hizentra can be dosed daily up to every 2 weeks, using an infusion pump and small needle(s).
Step-by-Step Instructions for Self-administering Hizentra provide a useful tool for patients new to this treatment method.Download the Infusion Guide