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Now Approved for CIDP

In adults with chronic inflammatory demyelinating polyneuropathy

Learn about Hizentra for CIDP

HCP Resources to Assist in SCIg Therapy Management

CSL Behring provides helpful resources to help you support your patients' use of Hizentra and address infusion problems if they occur.

Nursing Guide for Troubleshooting SCIg Administration

Nursing Guide for Troubleshooting SCIg Administration

A reference for nurses to troubleshoot issues that may occur before, during, or after infusion.

Download troubleshooting guide

Hizentra Progress Report

SCIg Therapy Progress Report

Keep track of your patient's progress during therapy and facilitate communication with your patient's healthcare team with this streamlined report.

Download progress report

Patient Discharge Instructions

Patient Discharge Instructions

This downloadable document covers essential information for any patient initiating SCIg therapy.

Download patient discharge instructions

Managing Common Infusion Issues

Your patients may experience issues during or after infusion with SCIg therapy. Use these clinical management troubleshooting techniques to possibly help resolve issues that may arise.8

Local Reaction

  • Assess for tape allergy—change to paper/hypoallergenic tape
  • Assess needle gauge—choose a needle that is consistent with volume being infused
  • Assess length of needle—may be too short and infusion may be intradermal
  • Assess site location—may not be penetrating subcutaneous tissue
  • Choose sites with appropriate amount of subcutaneous tissue
  • Avoid tracking IgG through intradermal tissue by not allowing drops of IgG on needle tip prior to needle insertion (prime dry)
  • Assess appropriateness of rotating sites based on previous tolerability
  • Consider use of topical anesthetic ointment
  • Avoid infusion into areas where the skin is tender, bruised, red, or hard. Avoid infusing into scars, stretch marks, or tattooed skin

Leaking at Infusion Site

  • Assess needle and catheter—ensure they are affixed securely and fully inserted
  • Assess placement—may be in location that is subject to movement; advise regarding selection of site
  • Assess length of subcutaneous needle—may be too short; suggest change
  • Assess rate of infusion volume—amount per site may be too great; adjust volume
  • Assess rate of infusion—adjust rate (rate may be too fast)

Discomfort With Needle

  • Assess needle length—may be too long and irritating to the infusion site
  • Try catheter that allows introducer needle to be removed or try another brand of SCIg set
  • Consider applying cold pack or topical anesthetic cream prior to insertion

Infusion Issues

  • Assess product storage—Hizentra is ready to use at room temperature; no refrigeration required
  • Assess volume per site, rate of infusion, and number of sites, or adjust infusion regimen
  • Check manufacturer's instructions for pump setting, correct selection of tubing size and length to match infusion rates; check pump function, battery function, etc
  • Arrange observation of patient technique (specialty pharmacy provider or office visit)

Click here for a printer-friendly version of these common issues.

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