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About Hizentra

Benefits of Hizentra

What makes Hizentra
unique for CIDP treatment?

Benefits of Hizentra

Infusion flexibility

You and your doctor can decide where you can infuse, and you won't have to adjust or cancel your plans due to IV infusion appointments.

Travel may be easier with Hizentra Prefilled Syringes, too.

Ig without the IV

You infuse Hizentra just under the skin, not into a vein, after training from your doctor. This means another option for people who need a port, or who are having trouble finding a vein or keeping their veins healthy.

Fewer systemic side effects

In clinical trials, people reported fewer systemic side effects (like headache and nausea) per infusion with Hizentra than with IVIg. With Hizentra, the most common side effects were redness, swelling, itching, and/or bruising at the infusion site; headache; chest, joint or back pain; diarrhea; tiredness; cough; rash; itching; fever, nausea, and vomiting. These are not the only side effects possible.

Subcutaneous Ig (SCIg) is strongly recommended by the EAN/PNS* medical guideline as a CIDP maintenance treatment option

*The European Academy of Neurology (EAN) and Peripheral Nerve Society (PNS) are two independent, international organizations of scientists, physicians, and other healthcare providers working together to investigate and treat neurological conditions and promote excellence leading to better care and outcomes.

Simpler infusions

How do I infuse?

Hizentra has been making prefilled syringes available for over 5 years to simplify the infusion process with:

The first and only lg with the convenience of prefilled syringes, so you can get back to everyday living

Watch a video to learn more about prefilled syringes

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Patient talking to their CIDP healthcare provider

Nurse assistance

Infusion help at home

Join today for personalized support on your self-infusion journey. This includes helping you get your Hizentra, explaining the self-administration process, and providing information about financial and other important resources.

Enroll now

Real patient stories

Meet
Stephanie

Patient advocate living with CIDP

Her CIDP diagnosis felt overwhelming at first, and IVIg therapy posed challenges. Switching to Hizentra provided consistent Ig levels, helping her maintain energy and strength.

More stories
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Hizentra
Live Webinar Series

Join a free educational online program for people with CIDP and their caregivers

Register for a live webinar
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CIDP
Doctor Discussion Guide

Download the guide and discuss Hizentra with your doctor today

Download
Hizentra Connect℠ logo

Savings
and support

From in-home nurse training visits to financial support and insurance navigation, free help is available so you can live confidently.

To learn more, call 1-877-355-4447 to enroll, Mon–Fri, 8 AM–8 PM ET. Or, you can start your enrollment online today.

Learn more about proven protection

Important Safety Information

WARNING: Thrombosis (blood clots) can occur with immune globulin products, including Hizentra. Risk factors can include: advanced age, prolonged immobilization, a history of blood clotting or hyperviscosity (blood thickness), use of estrogens, installed vascular catheters, and cardiovascular risk factors.

If you are at high risk of blood clots, your doctor will prescribe Hizentra at the minimum dose and infusion rate practicable and will monitor for signs of clotting events and hyperviscosity. Always drink sufficient fluids before infusing Hizentra.

See your doctor for a full explanation, and the full prescribing information for complete boxed warning.

Hizentra®, Immune Globulin Subcutaneous (Human), 20% Liquid, is a prescription medicine used to treat:

  • Primary immune deficiency (PI) in patients 2 years and older
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) in adults

Treatment with Hizentra might not be possible if your doctor determines you have hyperprolinemia (too much proline in the blood), or are IgA-deficient with antibodies to IgA and a history of hypersensitivity. Tell your doctor if you have previously had a severe allergic reaction (including anaphylaxis) to the administration of human immune globulin. Tell your doctor right away or go to the emergency room if you have hives, trouble breathing, wheezing, dizziness, or fainting. These could be signs of a bad allergic reaction.

Inform your doctor of any medications you are taking, as well as any medical conditions you may have had, especially if you have a history of diseases related to the heart or blood vessels, or have been immobile for some time. Inform your physician if you are pregnant or nursing, or plan to become pregnant.

Infuse Hizentra under your skin only; do not inject into a blood vessel.

Self-administer Hizentra only after having been taught to do so by your doctor or other healthcare professional, and having received dosing instructions for treating your condition.

Immediately report to your physician any of the following symptoms, which could be signs of serious adverse reactions to Hizentra:

  • Reduced urination, sudden weight gain, or swelling in your legs (possible signs of a kidney problem).
  • Pain and/or swelling or discoloration of an arm or leg, unexplained shortness of breath, chest pain or discomfort that worsens on deep breathing, unexplained rapid pulse, or numbness/weakness on one side of the body (possible signs of a blood clot).
  • Bad headache with nausea; vomiting; stiff neck; fever; and sensitivity to light (possible signs of meningitis).
  • Brown or red urine; rapid heart rate; yellowing of the skin or eyes; chest pains or breathing trouble; fever over 100°F (possible symptoms of other conditions that require prompt treatment).

Hizentra is made from human blood. The risk of transmission of infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent and its variant (vCJD), cannot be completely eliminated.

The most common side effects in the clinical trials for Hizentra include redness, swelling, itching, and/or bruising at the infusion site; headache; chest, joint or back pain; diarrhea; tiredness; cough; rash; itching; fever, nausea, and vomiting. These are not the only side effects possible. Tell your doctor about any side effect that bothers you or does not go away.

Before receiving any vaccine, tell immunizing physician if you have had recent therapy with Hizentra, as effectiveness of the vaccine could be compromised.

Please see full prescribing information for Hizentra, including boxed warning and the patient product information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You can also report side effects to CSL Behring's Pharmacovigilance Department at 1-866-915-6958.

View information about Hizentra for:
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