Convenient dosing lets you plan treatment around your life, instead of planning your life around treatment.
Prefilled Syringes
Explore the ways Hizentra Prefilled Syringes can simplify infusion setup vs. vials, saving time and effort
Watch the video or visit the self-administration page for a full instructional video
Be sure to get proper training from your healthcare provider before self-infusing Hizentra.
Flexible dosing
Hizentra offers adjustable dosing, so be sure to frequently update your doctor about how you're feeling so your doctor can personalize your treatment and identify the dose that works best for you.
EAN/PNS* medical guideline recommends adjusting subcutaneous immunoglobulin (SCIg) dose according to individual treatment response
*The European Academy of Neurology (EAN) and Peripheral Nerve Society (PNS) are two independent, international organizations of scientists, physicians, and other healthcare providers working together to investigate and treat neurological conditions and promote excellence leading to better care and outcomes.
Infusion time may be shorter or longer depending on the dose and frequency your doctor has prescribed for you.
You and your neurologist can create your Hizentra dosing schedule based on:
Hizentra Prefilled Syringes (PFS) give you proven protection with a first and only for Ig
Insights from a CSL-sponsored Harris Poll survey†
†In an online survey, at least 48 of 53 people with CIDP who self-infused Ig in prefilled syringes were very/somewhat satisfied on all measures mentioned.
Real patient stories
Watch Arthur experience the freedom and simplicity of using Hizentra Prefilled Syringes for CIDP maintenance.
Patient profiles
Richard is a business manager with a wife and two sons. The ups and downs associated with IVIg infusions brought physical challenges, affecting his ability to work and spend time with his family. Switching to Hizentra provided consistent Ig levels, which helped him maintain his energy and strength.
Based on a dose of 0.4 g/kg.
James is a software developer with a wife and teenage daughter. After hearing about the multiple systemic side effects (like headache and nausea) James experienced after every IVIg infusion and how they affected his work and family life, his doctor decided to put James on Hizentra. He finds time every weekend to relax at home and infuse his Hizentra.
Based on a dose of 0.2 g/kg.
Alice is a retired engineer who leads a quiet and relaxed life. She was tired of nurses not finding her veins and didn't want a port put in, so she talked to her doctor and started Hizentra. She now infuses at home once a week with the assistance of her caregiver.
Based on a weekly dose of 0.2 g/kg.
Miguel is an artist and part-time teacher who required frequent IV infusions to manage his disease. His frequent trips to the IV clinic were also a hassle. So he asked his doctor about Hizentra. They decided self-infusing at home on his own schedule was right for him. More frequent infusions mean less volume per infusion, letting him infuse in just about an hour. After discussing with his doctor, Miguel prefers prefilled syringes because he has difficulty drawing from vials.
Based on a weekly dose of 0.4 g/kg
Allison is a working mother with 3 young children. After talking with her doctor, she chose Hizentra so she could fit her infusions around her busy work and home schedule. Allison asked her doctor about appropriate places to infuse, and now she can decide where and when she self-infuses with ready-to-use prefilled syringes. She needs a dosing schedule that won't get in the way of work and taking care of her kids.
Based on a weekly dose of 0.4 g/kg.
*Infusion times may vary and are dependent on the pump brand and type of syringe used.
†Hypothetical case studies use recommended dose and labeled initial rate and volume per site, as well as maximum number of infusion sites. Photos do not depict actual patients.
WARNING: Thrombosis (blood clots) can occur with immune globulin products, including Hizentra. Risk factors can include: advanced age, prolonged immobilization, a history of blood clotting or hyperviscosity (blood thickness), use of estrogens, installed vascular catheters, and cardiovascular risk factors.
If you are at high risk of blood clots, your doctor will prescribe Hizentra at the minimum dose and infusion rate practicable and will monitor for signs of clotting events and hyperviscosity. Always drink sufficient fluids before infusing Hizentra.
See your doctor for a full explanation, and the full prescribing information for complete boxed warning.
Hizentra®, Immune Globulin Subcutaneous (Human), 20% Liquid, is a prescription medicine used to treat:
Treatment with Hizentra might not be possible if your doctor determines you have hyperprolinemia (too much proline in the blood), or are IgA-deficient with antibodies to IgA and a history of hypersensitivity. Tell your doctor if you have previously had a severe allergic reaction (including anaphylaxis) to the administration of human immune globulin. Tell your doctor right away or go to the emergency room if you have hives, trouble breathing, wheezing, dizziness, or fainting. These could be signs of a bad allergic reaction.
Inform your doctor of any medications you are taking, as well as any medical conditions you may have had, especially if you have a history of diseases related to the heart or blood vessels, or have been immobile for some time. Inform your physician if you are pregnant or nursing, or plan to become pregnant.
Infuse Hizentra under your skin only; do not inject into a blood vessel.
Self-administer Hizentra only after having been taught to do so by your doctor or other healthcare professional, and having received dosing instructions for treating your condition.
Immediately report to your physician any of the following symptoms, which could be signs of serious adverse reactions to Hizentra:
Hizentra is made from human blood. The risk of transmission of infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent and its variant (vCJD), cannot be completely eliminated.
The most common side effects in the clinical trials for Hizentra include redness, swelling, itching, and/or bruising at the infusion site; headache; chest, joint or back pain; diarrhea; tiredness; cough; rash; itching; fever, nausea, and vomiting. These are not the only side effects possible. Tell your doctor about any side effect that bothers you or does not go away.
Before receiving any vaccine, tell immunizing physician if you have had recent therapy with Hizentra, as effectiveness of the vaccine could be compromised.
Please see full prescribing information for Hizentra, including boxed warning and the patient product information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
You can also report side effects to CSL Behring's Pharmacovigilance Department at 1-866-915-6958.
