Infusion management Infusion management

Resources to help manage your patients’ self-infusions

CSL Behring helps you support your patients with essential resources that assist with Hizentra management and address infusion issues if they occur.

Considerations for managing common infusion issues

Your patients may experience issues during or after infusion with SCIg therapy. Consider these clinical management troubleshooting techniques to possibly help resolve issues that may arise.1

Local reaction

  • Assess for tape allergy—change to paper/hypoallergenic tape
  • Assess needle gauge—choose a needle that is consistent with volume being infused2
  • Assess length of needle—avoid infusion into the muscle or intradermal tissues
  • Assess site location—may not be penetrating subcutaneous tissue
  • Choose sites with appropriate amount of subcutaneous tissue
  • Reinforce dry priming—avoid tracking IgG through intradermal tissue by not allowing drops of IgG on needle tip prior to needle insertion
  • Assess appropriateness of rotating sites based on previous tolerability
  • Consider use of topical anesthetic
  • Avoid infusing into areas where the skin is tender, bruised, red, or hard. Avoid infusing into scars or stretch marks

Leaking at infusion site

  • Assess needle—ensure it is affixed securely and fully inserted
  • Assess placement—may be in location that is subject to movement; advise regarding selection of site
  • Assess length of subcutaneous needle—may be too short; suggest change
  • Assess total volume per infusion site—amount per site may be too great; adjust volume
  • Assess rate of infusion—adjust rate (rate may be too fast)2

Discomfort with needle

  • Assess needle length—may be too long and irritating to the infusion site
  • Consider applying cold pack or topical anesthetic prior to insertion

Infusion issues

  • Assess product storage—Hizentra is ready to use at room temperature; no refrigeration required
  • Assess volume per site, rate of infusion, and number of sites, or adjust infusion regimen
  • Check manufacturer’s instructions for pump setting, correct selection of tubing size and length to match infusion rates; check pump function, battery function, etc
  • Arrange observation of patient technique (specialty pharmacy provider or office visit)

Additional resources to help patients manage therapy

CSL Behring is committed to partnering with you, providing a variety of support services for you and your patients. Explore these links for more information.

Hizentra vial and prefilled syringe

Ask a CSL Infusion Science Specialist Nurse for insight, information, and training regarding administration of Hizentra. Take advantage of this service, which is available exclusively for healthcare professionals.

Register for help from an Infusion Science Specialist Nurse
Hizentra support headphone icon

Proper self-infusion training from the start can help patients avoid issues going forward.

Helpful resources include:

  • Welcome kit for new patients
  • Informative brochures
  • Hizentra App to track infusions and more
Patient resources
Hizentra connect logo

Hizentra ConnectSM is a comprehensive resource center to help you and your patients.

Exclusive resources include:

  • In-home nurse training
  • Infusion equipment at no cost
  • Free Trial program with a month’s supply of product to see if Hizentra is right for you
Hizentra Connect support
SHARE Nurse training for PI and CIDP

Optimize patient care with nurse education and training on SCIg administration through the SHARE Nurse Training Center.

SHARE nurse training
FAQ Icon

More information about helping patients get started on Hizentra may be found in our FAQ section.

Frequently asked questions

References: 1. Murphy E, Burton J, Riley P. Nursing approaches to a novel subcutaneous immunoglobulin therapy. Infusion. 2007;13:1-8. 2. Younger ME, Aro L, Blouin W, et al. Nursing Guidelines for Administration of Immunoglobulin Replacement Therapy. J Infusion Nursing. 2013;36(1):58-68.

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