Managing Common Infusion Issues
Your patients may experience issues during or after infusion with SCIg therapy. Use these clinical management troubleshooting techniques to possibly help resolve issues that may arise.13
- Assess for tape allergy—change to paper/hypoallergenic tape
- Assess needle gauge—choose a needle that is consistent with volume being infused
- Assess length of needle—may be too short and infusion may be intradermal
- Assess site location—may not be penetrating subcutaneous tissue
- Choose sites with appropriate amount of subcutaneous tissue
- Avoid tracking IgG through intradermal tissue by not allowing drops of IgG on needle tip prior to needle insertion (prime dry)
- Assess appropriateness of rotating sites based on previous tolerability
- Consider use of topical anesthetic ointment
- Avoid infusion into areas where the skin is tender, bruised, red, or hard. Avoid infusing into scars or stretch marks
Leaking at Infusion Site
- Assess needle and catheter—ensure they are affixed securely and fully inserted
- Assess placement—may be in location that is subject to movement; advise regarding selection of site
- Assess length of subcutaneous needle—may be too short; suggest change
- Assess rate of infusion volume—amount per site may be too great; adjust volume
- Assess rate of infusion—adjust rate (rate may be too fast)
Discomfort With Needle
- Assess needle length—may be too long and irritating to the infusion site
- Try catheter that allows introducer needle to be removed or try another brand of SCIg set
- Consider applying cold pack or topical anesthetic cream prior to insertion
- Assess product storage—Hizentra is ready to use at room temperature; no refrigeration required
- Assess volume per site, rate of infusion, and number of sites, or adjust infusion regimen
- Check manufacturer's instructions for pump setting, correct selection of tubing size and length to match infusion rates; check pump function, battery function, etc
- Arrange observation of patient technique (specialty pharmacy provider or office visit)
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Additional Resources for HCPs to Help Patients Manage Therapy
CSL Behring is committed to helping you help your patients effectively self-administer Hizentra. Explore these links for more information.
Optimize patient care with nurse education and training on SCIg administration through the SHARE Nurse Training Center.
Because good initial self-infusion training can help patients avoid problems going forward, we offer a variety of resources to help patients become adept with their therapy.